Advancing

oVARIAN CANCER research

Our goal

Understanding the dynamics of the
spatial tumor microenvironment

We want to understand the dynamics of the tumor microenvironment using systems oncology approaches. Our research focuses on developing prognostic and predictive biomarkers and new therapeutic approaches to improve the treatment and survival of patients with high-grade serous ovarian cancer (HGSC).

We are interested in

Immune cell-subtypes
Functional and spatial states
Cell-cell interactions

That contribute to spatial plasticity in HGSC

Unique cross-disciplinary approaches

Close to the clinic

We work closely with clinicians, collecting tumor tissue samples as well as clinical data of ovarian cancer patients at Helsinki University Women’s Hospital

Functional assays in tumor organoids

To assay the molecular mediators and spatial effectors of immune recognition before and after DNA damaging agents and immunotherapies

Multiplexed immunofluorescence (tCyCIF) and bioinformatic analysis

To shed light on the critical immune-regulatory pathways in HGSC molecular subtypes

Our mission is to advance scientific knowledge and make impactful contributions to enable precision oncology and improve the lives of cancer patients

More about us

Based in Finland

We research ovarian cancer in Finland. We are part of the prestigious Faculty of Medicine of the University of Helsinki, ranked as one of the best in the world