Our goal
Understanding the dynamics of the
spatial tumor microenvironment
We want to understand the dynamics of the tumor microenvironment using systems oncology approaches. Our research focuses on developing prognostic and predictive biomarkers and new therapeutic approaches to improve the treatment and survival of patients with high-grade serous ovarian cancer (HGSC).
We are interested in
Immune cell-subtypes
Functional and spatial states
Cell-cell interactions
That contribute to spatial plasticity in HGSC
Unique cross-disciplinary approaches
Close to the clinic
We work closely with clinicians, collecting tumor tissue samples as well as clinical data of ovarian cancer patients at Helsinki University Women’s Hospital
Functional assays in tumor organoids
To assay the molecular mediators and spatial effectors of immune recognition before and after DNA damaging agents and immunotherapies
Multiplexed immunofluorescence (tCyCIF) and bioinformatic analysis
To shed light on the critical immune-regulatory pathways in HGSC molecular subtypes
We are recruiting! Nowadays we are looking for a Postdoc, PhD and Master’s students to join our lab
More about us
Diverse team
Our lab-members have a wide variety of educational backgrounds and come from multiple countries from all around the globe
Funding
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